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LSD1 is regulating the 1, 25(OH)2D effects brought on by target genes by functioning as a coactivator and corepressor of VDR action

The Agencys Center for Drug Evaluation and Research (CDER) has accepted a Letter of Intent for use of liver stiffness measurement by vibration-controlled transient elastography (VCTE) as a reasonably likely surrogate endpoint for all-cause mortality or liver-related events in adults with non-cirrhotic metabolic dysfunction-associated steatohepatitis (MASH) with moderate to advanced liver fibrosis

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